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1

Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors

Oliver Rackham, Anne-Marie J. Shearwood, Ross Thyer, Elyshia McNamara, Stefan M.K. Davies, Bernard A. Callus, Antonio Miranda-Vizuete, Susan J. Berners-Price, Qing Cheng, Elias S.J. Arnér, Aleksandra

Journal:

Free Radical Biology and Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 993 KB

english, 2011

2

The Mammalian Testis-Specific Thioredoxin System

Miranda-Vizuete, Antonio, Sadek, Christine M., Jiménez, Alberto, Krause, William J., Sutovsky, Peter, Oko, Richard

Journal:

Antioxidants & Redox Signaling

Année:

2004

Langue:

english

Fichier:

PDF, 851 KB

english, 2004

3

Divergence in enzyme regulation between Caenorhabditis elegans and human tyrosine hydroxylase, the key enzyme in the synthesis of dopamine

Calvo, Ana C., Pey, Angel L., Miranda-Vizuete, Antonio, Døskeland, Anne P., Martinez, Aurora

Journal:

Biochemical Journal

Année:

2011

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2011

4

The cytoplasmic thioredoxin system in Caenorhabditis elegans affords protection from methylmercury in an age-specific manner

Ruszkiewicz, Joanna A., de Macedo, Gabriel Teixeira, Miranda-Vizuete, Antonio, Teixeira da Rocha, João B., Bowman, Aaron B., Bornhorst, Julia, Schwerdtle, Tanja, Aschner, Michael

Journal:

NeuroToxicology

Année:

2018

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2018

5

Thioredoxin-related protein-1 induced by prostaglandin E2

Antonio Miranda-Vizuete

Journal:

International Journal of Cancer

Année:

2006

Langue:

english

Fichier:

PDF, 423 KB

english, 2006

6

Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells

Christine M. Sadek, Anastasios E. Damdimopoulos, Markku Pelto-Huikko, Jan-Åke Gustafsson, Giannis Spyrou, Antonio Miranda-Vizuete

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 6.50 MB

english, 2001

7

Identification and distribution of thioredoxin-like 2 as the antigen for the monoclonal antibody MC3 specific to colorectal cancer

Yuanyuan Lu, Xin Wang, Zhenxiong Liu, Bin Jin, Dake Chu, Huihong Zhai, Faming Zhang, Kai Li, Gui Ren, Antonio Miranda-Vizuete, Xuegang Guo, Daiming Fan

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 558 KB

english, 2008

8

The txl1+ gene from Schizosaccharomyces pombe encodes a new thioredoxin-like 1 protein that participates in the antioxidant defence against tert-butyl hydroperoxide

Alberto Jiménez, Laura Mateos, José R. Pedrajas, Antonio Miranda-Vizuete, José L. Revuelta

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 275 KB

english, 2007

9

A genome-wide survey of human thioredoxin and glutaredoxin family pseudogenes

Giannis Spyrou, William Wilson, Alicia C. Padilla, Arne Holmgren, Antonio Miranda-Vizuete

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 435 KB

english, 2001

10

Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy

Perez-Jimenez, Raul, Li, Jingyuan, Kosuri, Pallav, Sanchez-Romero, Inmaculada, Wiita, Arun P, Rodriguez-Larrea, David, Chueca, Ana, Holmgren, Arne, Miranda-Vizuete, Antonio, Becker, Katja

Journal:

Nature Structural and Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 564 KB

english, 2009

11

Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy

Perez-Jimenez, Raul, Li, Jingyuan, Kosuri, Pallav, Sanchez-Romero, Inmaculada, Wiita, Arun P, Rodriguez-Larrea, David, Chueca, Ana, Holmgren, Arne, Miranda-Vizuete, Antonio, Becker, Katja

Journal:

Nature Structural and Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 134 KB

english, 2009

12

The human thioredoxin reductase-1 splice variant TXNRD1_v3 is an atypical inducer of cytoplasmic filaments and cell membrane filopodia

Pauliina E. Damdimopoulou, Antonio Miranda-Vizuete, Elias S.J. Arnér, Jan-Åke Gustafsson, Anastasios E. Damdimopoulos

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2009

Langue:

english

Fichier:

PDF, 755 KB

english, 2009

13

cDNA cloning, expression and chromosomal localization of the mouse mitochondrial thioredoxin reductase gene

Antonio Miranda-Vizuete, Anastasios E Damdimopoulos, Giannis Spyrou

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

1999

Langue:

english

Fichier:

PDF, 335 KB

english, 1999

14

Human mitochondrial thioredoxin reductase : cDNA cloning, expression and genomic organization

Antonio Miranda-Vizuete, Anastasios E. Damdimopoulos, José Rafael Pedrajas, Jan-Åke Gustafsson, Giannis Spyrou

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 1.30 MB

english, 1999

15

Molecular Cloning and Expression of a cDNA Encoding a Human Thioredoxin-like Protein

Antonio Miranda-Vizuete, Jan-Åke Gustafsson, Giannis Spyrou

Journal:

Biochemical and Biophysical Research Communications

Année:

1998

Langue:

english

Fichier:

PDF, 922 KB

english, 1998

16

Absolute mRNA levels and transcriptional regulation of the mouse testis-specific thioredoxins

Alberto Jiménez, María J. Prieto-Álamo, Carlos A. Fuentes-Almagro, Juan Jurado, Jan-Åke Gustafsson, Carmen Pueyo, Antonio Miranda-Vizuete

Journal:

Biochemical and Biophysical Research Communications

Année:

2005

Langue:

english

Fichier:

PDF, 296 KB

english, 2005

17

The thioredoxin TRX-1 regulates adult lifespan extension induced by dietary restriction in Caenorhabditis elegans

Juan Carlos Fierro-González, María González-Barrios, Antonio Miranda-Vizuete, Peter Swoboda

Journal:

Biochemical and Biophysical Research Communications

Année:

2011

Langue:

english

Fichier:

PDF, 474 KB

english, 2011

18

Lifespan decrease in a Caenorhabditis elegans mutant lacking TRX-1, a thioredoxin expressed in ASJ sensory neurons

Antonio Miranda-Vizuete, Juan Carlos Fierro González, Gabriele Gahmon, Jan Burghoorn, Plácido Navas, Peter Swoboda

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 339 KB

english, 2006

19

Characterization of human thioredoxin-like-1: Potential involvement in the cellular response against glucose deprivation

Alberto Jiménez, Markku Pelto-Huikko, Jan-Åke Gustafsson, Antonio Miranda-Vizuete

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 458 KB

english, 2006

20

Purification and characterization of Δ3Trx-1, a splicing variant of human thioredoxin-1 lacking exon 3

Alberto Jiménez, Antonio Miranda-Vizuete

Journal:

Protein Expression and Purification

Année:

2003

Langue:

english

Fichier:

PDF, 290 KB

english, 2003

21

The Characterization of the Caenorhabditis elegans Mitochondrial Thioredoxin System Uncovers an Unexpected Protective Role of Thioredoxin Reductase 2 in β-Amyloid Peptide Toxicity

Cacho-Valadez, Briseida, Muñoz-Lobato, Fernando, Pedrajas, José Rafael, Cabello, Juan, Fierro-González, Juan Carlos, Navas, Plácido, Swoboda, Peter, Link, Chris D., Miranda-Vizuete, Antonio

Journal:

Antioxidants & Redox Signaling

Année:

2012

Langue:

english

Fichier:

PDF, 1.97 MB

english, 2012

22

Evidence for intriguingly complex transcription of human thioredoxin reductase 1

Anna-Klara Rundlöf, Magnus Janard, Antonio Miranda-Vizuete, Elias S.J. Arnér

Journal:

Free Radical Biology and Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 652 KB

english, 2004

23

Selenium induces cholinergic motor neuron degeneration in Caenorhabditis elegans

Annette O. Estevez, Catherine L. Mueller, Kathleen L. Morgan, Nathaniel J. Szewczyk, Luke Teece, Antonio Miranda-Vizuete, Miguel Estevez

Journal:

NeuroToxicology

Année:

2012

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2012

24

Tyrosol, a main phenol present in extra virgin olive oil, increases lifespan and stress resistance in Caenorhabditis elegans

Cañuelo, Ana, Gilbert-López, Bienvenida, Pacheco-Liñán, Pedro, Martínez-Lara, Esther, Siles, Eva, Miranda-Vizuete, Antonio

Journal:

Mechanisms of Ageing and Development

Année:

2012

Langue:

english

Fichier:

PDF, 709 KB

english, 2012

25

P4-233 Beta-amyloid oxidation of thioredoxin and glutaredoxin. A possible link between oxidative stress and apoptosis in Alzheimer's disease

Akterin, Susanne, Miranda-Vizuete, Antonio, Winblad, Bengt, Cowburn, Richard F., Cedazo-Mínguez, Angel

Journal:

Neurobiology of Aging

Année:

2004

Langue:

english

Fichier:

PDF, 370 KB

english, 2004

26

P3-383

Akterin, Susanne, Sandebring, Anna, Cowburn, Richard F., Miranda-Vizuete, Antonio, Jimanez, Alberto, Bogdanovic, Nenad, Winblad, Bengt, Cedazo-Manguez, Angel

Journal:

Alzheimer's & Dementia

Année:

2006

Langue:

english

Fichier:

PDF, 54 KB

english, 2006

27

High Throughput, Parallel Imaging and Biomarker Quantification of Human Spermatozoa by ImageStream Flow Cytometry

Buckman, Clayton, George, Thaddeus C., Friend, Sherree, Sutovsky, Miriam, Miranda-Vizuete, Antonio, Ozanon, Christophe, Morrissey, Phil, Sutovsky, Peter

Journal:

Systems Biology in Reproductive Medicine

Année:

2009

Langue:

english

Fichier:

PDF, 551 KB

english, 2009

28

Genomic Structure and Chromosomal Localization of Human Thioredoxin-Like Protein Gene ( txl )

Miranda-Vizuete, Antonio, Spyrou, Giannis

Journal:

Mitochondrial DNA

Année:

2000

Langue:

english

Fichier:

PDF, 755 KB

english, 2000

29

Cloning and Sequencing of Mouse Glutaredoxin (grx) cDNA

Miranda-vizuete, Antonio, Pedrajas, JosÉ Rafael, Damdimopoulos, Anastasios E., Spyrou, Giannis

Journal:

Mitochondrial DNA

Année:

1999

Langue:

english

Fichier:

PDF, 259 KB

english, 1999

30

Thioredoxin-Like Protein 2 Is Overexpressed in Colon Cancer and Promotes Cancer Cell Metastasis by Interaction with Ran

Lu, Yuanyuan, Zhao, Xiaodi, Li, Kai, Luo, Guanhong, Nie, Yongzhan, Shi, Yongquan, Zhou, Yi, Ren, Gui, Feng, Bin, Liu, Zhenxiong, Pan, Yan, Li, Ting, Guo, Xuegang, Wu, Kaichun, Miranda-Vizuete, Antonio

Journal:

Antioxidants & Redox Signaling

Année:

2013

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2013

31

Identification of the First Human Glutaredoxin Pseudogene Localized to Human Chromosome 20qll.2

Miranda-Vizuete, Antonio, Spyrou, Giannis

Journal:

Mitochondrial DNA

Année:

2001

Langue:

english

Fichier:

PDF, 380 KB

english, 2001

32

The Mitochondrial Thioredoxin System

Miranda-Vizuete, Antonio, Damdimopoulos, Anastasios E., Spyrou, Giannis

Journal:

Antioxidants & Redox Signaling

Année:

2000

Langue:

english

Fichier:

PDF, 948 KB

english, 2000

33

Identification of a Novel Thioredoxin-1 Pseudogene on Human Chromosome 10

Miranda-Vizuete, Antonio, Spyrou, Giannis

Journal:

Mitochondrial DNA

Année:

2000

Langue:

english

Fichier:

PDF, 248 KB

english, 2000

34

Selenoprotein TRXR-1 and GSR-1 are essential for removal of old cuticle during molting in Caenorhabditis elegans

Jörgen Stenvall, Juan Carlos Fierro-González, Peter Swoboda, Karunakar Saamarthy, Qing Cheng, Briseida Cacho-Valadez, Elias S. J. Arnér, Olof P. Persson, Antonio Miranda-Vizuete, Simon Tuck and Gary R

Journal:

Proceedings of the National Academy of Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2011

35

GLUTATHIONE IS THE RESOLVING THIOL FOR THIOREDOXIN PEROXIDASE ACTIVITY OF 1-CYS PEROXIREDOXIN WITHOUT BEING CONSUMED DURING THE CATALYTIC CYCLE

Pedrajas, José Rafael, McDonagh, Brian, Hernández-Torres, Francisco, Miranda-Vizuete, Antonio, González, Raul, Martínez-Galisteo, Emilia, Padilla, C. Alicia, Bárcena, José Antonio

Journal:

Antioxidants & Redox Signaling

Année:

2015

Langue:

english

Fichier:

PDF, 2.68 MB

english, 2015

36

Two Additional Glutaredoxins Exist in Escherichia coli: Glutaredoxin 3 is a Hydrogen Donor for Ribonucleotide Reductase in a Thioredoxin/Glutaredoxin 1 Double Mutant

Fredrik Åslund, Barbro Ehn, Antonio Miranda-Vizuete, Carmen Pueyo and Arne Holmgren

Journal:

Proceedings of the National Academy of Sciences

Année:

1994

Langue:

english

Fichier:

PDF, 1.40 MB

english, 1994

37

Caenorhabditis elegans AGXT-1 is a mitochondrial and temperature-adapted ortholog of peroxisomal human AGT1: New insights into between-species divergence in glyoxylate metabolism

Mesa-Torres, Noel, Calvo, Ana C., Oppici, Elisa, Titelbaum, Nicholas, Montioli, Riccardo, Miranda-Vizuete, Antonio, Cellini, Barbara, Salido, Eduardo, Pey, Angel L.

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Année:

2016

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2016

38

The novel oxidoreductase KDRF (KM-102-derived reductase-like factor) is identical with human thioredoxin reductase

MIRANDA-VIZUETE, Antonio, SPYROU, Giannis

Journal:

Biochemical Journal

Année:

1997

Langue:

english

Fichier:

PDF, 243 KB

english, 1997

39

Two isoforms of Saccharomyces cerevisiae glutaredoxin 2 are expressed in vivo and localize to different subcellular compartments

PEDRAJAS, José R., PORRAS, Pablo, MARTÍNEZ-GALISTEO, Emilia, PADILLA, C. Alicia, MIRANDA-VIZUETE, Antonio, BÁRCENA, J. Antonio

Journal:

Biochemical Journal

Année:

2002

Langue:

english

Fichier:

PDF, 265 KB

english, 2002

40

Caenorhabditis elegans as a model for understanding ROS function in physiology and disease

Miranda-Vizuete, Antonio, Veal, Elizabeth A.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 715 KB

english, 2017

41

Selenoprotein T is required for pathogenic bacteria avoidance in Caenorhabditis elegan s

Romanelli-Cedrez, Laura, Carrera, Inés, Otero, Lucía, Miranda-Vizuete, Antonio, Mariotti, Marco, Alkema, Mark J., Salinas, Gustavo

Journal:

Free Radical Biology and Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 1.63 MB

english, 2017

42

Insights Into the Differential Toxicological and Antioxidant Effects of 4-phenylchalcogenil-7-chloroquinolines in Caenorhabditis elegans

Salgueiro, Willian G., Goldani, Bruna S., Peres, Tanara V., Miranda-Vizuete, Antonio, Aschner, Michael, da Rocha, João Batista Teixeira, Alves, Diego, Ávila, Daiana S.

Journal:

Free Radical Biology and Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2017

43

The neuroprotective transcription factor ATF5 is decreased and sequestered into polyglutamine inclusions in Huntington’s disease

Hernández, Ivó H., Torres-Peraza, Jesús, Santos-Galindo, María, Ramos-Morón, Eloísa, Fernández-Fernández, M. Rosario, Pérez-Álvarez, María J., Miranda-Vizuete, Antonio, Lucas, José J.

Journal:

Acta Neuropathologica

Année:

2017

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2017

44

Intracellular Trafficking and Persistence of Acinetobacter baumannii Requires Transcription Factor EB

Parra-Millán, Raquel, Guerrero-Gómez, David, Ayerbe-Algaba, Rafael, Pachón-Ibáñez, Maria Eugenia, Miranda-Vizuete, Antonio, Pachón, Jerónimo, Smani, Younes, D'Orazio, Sarah E. F.

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 2.66 MB

english, 2018

45

The Thioredoxin TRX-1 Modulates the Function of the Insulin-Like Neuropeptide DAF-28 during Dauer Formation in Caenorhabditis elegans

Fierro-González, Juan Carlos, Cornils, Astrid, Alcedo, Joy, Miranda-Vizuete, Antonio, Swoboda, Peter, Nollen, Ellen

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 513 KB

english, 2011

46

Semen Levels of Spermatid-Specific Thioredoxin-3 Correlate with Pregnancy Rates in ART Couples

Buckman, Clayton, Ozanon, Christophe, Qiu, Jing, Sutovsky, Miriam, Carafa, Joyce Ann, Rawe, Vanesa Y., Manandhar, Gaurishankar, Miranda-Vizuete, Antonio, Sutovsky, Peter, Drevet, Joel R.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 3.33 MB

english, 2013

47

The cytoplasmic thioredoxin system in Caenorhabditis elegans affords protection from methylmercury in an age-specific manner

Ruszkiewicz, Joanna A., de Macedo, Gabriel Teixeira, Miranda-Vizuete, Antonio, Teixeira da Rocha, João B., Bowman, Aaron B., Bornhorst, Julia, Schwerdtle, Tanja, Aschner, Michael

Journal:

NeuroToxicology

Année:

2018

Fichier:

PDF, 1.21 MB

2018

48

Sex-Specific Response of Caenorhabditis elegans to Methylmercury Toxicity

Ruszkiewicz, Joanna A., Teixeira de Macedo, Gabriel, Miranda-Vizuete, Antonio, Bowman, Aaron B., Bornhorst, Julia, Schwerdtle, Tanja, Antunes Soares, Felix A., Aschner, Michael

Journal:

Neurotoxicity Research

Année:

2018

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2018

49

Sex-Specific Differences in Redox Homeostasis in Brain Norm and Disease

Ruszkiewicz, Joanna A., Miranda-Vizuete, Antonio, Tinkov, Alexey A., Skalnaya, Margarita G., Skalny, Anatoly V., Tsatsakis, Aristides, Aschner, Michael

Journal:

Journal of Molecular Neuroscience

Année:

2019

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2019

50

Epicatechin modulates stress-resistance in C. elegans via insulin/IGF-1 signaling pathway

Ayuda-Durán, Begoña, González-Manzano, Susana, Miranda-Vizuete, Antonio, Dueñas, Montserrat, Santos-Buelga, Celestino, González-Paramás, Ana M., Min, Kyung-Jin

Journal:

Année:

2019

Fichier:

PDF, 2.69 MB

2019